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PRE-ORDER Only - Available starting JUNE 23, 2022

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A film by Lisa Hepner and Guy Mossman

91 min.

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In 2011, Lisa Hepner and her husband Guy Mossman heard about a radical stem cell treatment for diabetes, a disease that, shockingly, kills more than five million people each year. Driven by a desire to cure Lisa of her own type 1 diabetes (T1D), the filmmakers were given unprecedented, real-time access to a clinical trial -- only the sixth-ever embryonic stem cell trial in the world. What follows is an intimate journey with the patients and scientists who risk everything to be first.

The Human Trial interweaves the stories of the patients who have borne the physical and financial burdens of type 1 diabetes (T1D) — with the researchers who epitomize the struggle of innovating cures. Director Lisa Hepner — whose own T1D fuels her search for a cure — becomes the bridge between these two worlds, painting an emotional portrait of what it takes to push medical innovation forward. The narrative arc of The Human Trial is the clinical trial itself. For seven years, Lisa and Guy embedded themselves with a biotech company in San Diego. They filmed the researchers’ triumphs and failures in the lab, following them around the globe as they raised money to keep their trial going. In parallel, the filmmaking team followed two patients, the self-described “guinea pigs” at the University of Minnesota. More than a decade in the making, the first-person, verité film is about science, but it’s also an emotional, multilayered quest that transcends the genre. It’s about believing that the good of the many outweigh the good of the few. It’s about innovating in ways we didn’t think possible.

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